Faculty: Chemistry

Offer details

TECHNICAL OFFER
no 052/2018
SECTOR
pharmacy, medicine, anticancer therapies
AUTHORS
prof. Adam Lesner
dr Magdalena Wysocka
FACULTY
Chemistry

Commercialization

Licencja
, Sprzedaż praw własności
, Spin off
IP PROTECTION
The invention is the subject of patent protection: PL: Pat.238871
TECHNOLOGY READINESS LEVEL
TRL 4
Technology validated in laboratory conditions

Carrier of active substance to increase permeability into the cell nucleus

Nowadays, the use of cell membrane-penetrating peptides is part of clinical trials for the treatment of dermatitis, cancer and cardiac failure.

A peptidomimetic containing a fluorescent grouping in the sequence (5/6-carboxyfluorescein) may find application in the pharmaceutical industry and, in particular, facilitate the penetration of therapeutic substances used in anticancer therapy into the nucleus cell.

The active substance, which contains a fluorescent grouping in the sequence (5/6-carboxyfluorescein), is intended for use in the pharmaceutical industry as an ingredient in drugs with a long time to penetrate the nucleus cell, making it possible to accelerate this process.

The developed method allows the introduction of the drug active substance in a more targeted manner, with little risk of destroying a healthy cell. The use of the innovative substance has the positive effect of accelerating the cancer treatment process.

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