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Diagnostic set for detection of rabbit haemorrhagic disease virus in animal serum – Technology Transfer Office

Faculty: Biotechnology UG&MUG

Offer details

TECHNICAL OFFER
nr 029/2017/2
SECTOR
rabbit farming, veterinary medicine
AUTHORS
prof. Bogusław Szewczyk
Beata Gromadzka
Andrzej Fitzner
Andrzej Kęsy
FACULTY
Biotechnology UG&MUG

Commercialization

Licence, Sale of property rights, Partnership for further research and commercialisation
TECHNOLOGY READINESS LEVEL
TRL 4
Technology validated in laboratory conditions

Diagnostic set for detection of rabbit haemorrhagic disease virus in animal serum

Zestaw diagnostyczny do badania surowic zwierząt na obecność wirusa RHD

Rabbit haemorrhagic disease (RHD), also known as rabbit calicivirus disease (RCD), is a viral disease that may be acute or peracute, with a very high mortality rate reaching 100% of affected population.

High mortality and the neccessity of culling not only infected individuals, but even animals suspected of being in contact with infected ones, makes RHD a serious veterinary hazard for both farmers and rabbit owners. Aforementionned hazards result in a high demand for diagnostic methods which allow for precise identification of diseased animals and their differentiation from healthy individuals.

Developed technology allows for monospecific immune sera generated by vaccinating laboratory animals with purified recombinant RHD virus antigen (VLP RHDV)  to be used in ELISA tests, ensuring high sensitivity, specificity and reproducibility of obtained results.

The use of a control system consisting of a positive antigen and a negative control of the virus, as well as samples of control sera, allows for quick and accruate classification of investigated samples as either positive or negative. This in turn allows one to distinguish between healthy animals and infected individuals, without the need to cull entire population.

Technology related to offer no. 030/2017/1

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