The invention concerns an antibacterial mixture containing 3,5-dihydroxy-2-methyl-1,4-naphthoquinone (droserone) and silver nanoparticles, exhibiting synergistic bactericidal activity against resistant Pseudomonas aeruginosa strains.
The use of nanosilver enables activation of droserone’s antibacterial properties and restores bacterial susceptibility.
The mixture shows a strong synergistic effect, significantly reducing the effective concentrations of both components while maintaining high biological efficacy.
The invention offers a promising approach for treating P. aeruginosa infections of the skin and wounds, including multidrug-resistant strains.
Application:
- Topical preparations for treating skin and wound infections caused by Staphylococcus aureus
- Sntiseptic and disinfectant agents in medical and veterinary use,
- Component of wound dressings and healing-support formulations.
