The invention concerns a method for obtaining an extract from in vitro-cultured tissues of Drosera gigantea. The extract contains active secondary metabolites with strong antibacterial potential and low levels of toxic naphthoquinones (e.g. plumbagin <100 µg/g FM).
Two extraction variants are proposed: aqueous and 50% tetrahydrofuran solution. The process includes purification, freezing, microwave or ultrasonic extraction, filtration and lyophilization to obtain a dry residue rich in metabolites.
The extract shows strong activity against Gram-positive bacteria (S. aureus, E. faecalis, A. baumannii) and moderate activity vs Gram-negative strains (E. coli, P. aeruginosa, K. pneumoniae). It is non-toxic to model organisms (C. elegans) and can be used in pharmaceutical, cosmetic and veterinary products as a natural alternative or additive to antiseptic formulations.
Zastosowanie:
- Dermatological and veterinary preparations with antibacterial properties,
- Ingredient in protective and regenerating cosmetics,
- Alternative to antibiotics in the treatment of local skin infections.
